Effects of hemodialysis on bone mineral as followed by using neutron activation analysis.

The purpose of the study was to bring a contribution to the knowledge of physiology and pathophysiology of the bone mineral heteroionic exchange with respect to sodium ions and metabolic diseases, particularly bone diseases. The instrumental neutron activation analysis was employed to follow the ratio of contents Na/Ca in bone samples from dialyzed patients. A formerly elaborated method for the determination of the Na/Ca ratio in undecalcified bone tissue sections obtained from material embedded in polymethylmethacrylate was used. In the reference group the Na/Ca ratio was of 0.021 +/- 0.003, that in patients with the renal osteopathy was of 0.030 +/- 0.007. Results obtained in patients with different types of the renal osteopathy depending on the intensity of the impairment were discussed.