International surgery · 2012
Primary hepatic cancers with multiple pathologic features in a patient with hepatitis C: report of a case.
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Oshima Go, Shinoda Masahiro, Tanabe Minoru, Masugi Yohei, Ueno Akihisa, Takano Kiminori, Kitago Minoru, Itano Osamu, Kawachi Shigeyuki, Ohara Kentaro, Oda Masaya, Tanimoto Akihiro, Sakamaoto Michiie, Kitagawa Yuko
Аннотация
We report a case of multiple primary hepatic cancers exhibiting different pathologic features coexisting in a patient with chronic hepatitis C. Computed tomography showed 2 tumors in segment 8, 20 mm (S8-A) and 5 mm (S8-B) in diameter, and a 10-mm tumor in segment 6 (S6). Based on the images, the S8-A lesion was diagnosed as cholangiocellular carcinoma or combined hepatocellular carcinoma and cholangiocarcinoma (combined HCC-CC). The other 2 tumors were diagnosed as HCC. The patient underwent partial resections of segments 6 and 8. We found 2 more tumors (S8-C was 6 mm in diameter and S8-D was 4 mm) in the resected segment 8 specimen. Histopathologic examination revealed that the S8-A and S8-C tumors were combined HCC-CC, the S8-B and S6 lesions were scirrhous HCC, and the S8-D tumor was an early HCC. This is a very rare case in which different hepatic cancers with multiple pathologic features coexisted.