Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology · 2006
Fatal cor pulmonale caused by pulmonary tumor microembolism in a patient with occult gastric cancer.
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Corradi Domenico, Mormandi Francesca, Tanzi Giulia, Ricci Roberto, Bini Paola, Giuliotti Sara, Zompatori Maurizio
Аннотация
BACKGROUND: A fatal pulmonary tumor microembolism is rarely caused by an occult gastric cancer.
METHODS AND RESULTS: We report the case of a 40-year-old woman who died after 3 days of progressive dyspnea, cough, and pulmonary hypertension. Postmortem examination demonstrated the presence of an occult diffuse-type gastric carcinoma, which had caused emboli in about 80% of small pulmonary arteries and arterioles. Despite an interatrial defect in the fossa ovalis, no parenchymal metastases were documented.
CONCLUSION: Pulmonary tumor microembolism may be suspected in patients complaining of unexplained progressive dyspnea and who develop acute or subacute cor pulmonale.
METHODS AND RESULTS: We report the case of a 40-year-old woman who died after 3 days of progressive dyspnea, cough, and pulmonary hypertension. Postmortem examination demonstrated the presence of an occult diffuse-type gastric carcinoma, which had caused emboli in about 80% of small pulmonary arteries and arterioles. Despite an interatrial defect in the fossa ovalis, no parenchymal metastases were documented.
CONCLUSION: Pulmonary tumor microembolism may be suspected in patients complaining of unexplained progressive dyspnea and who develop acute or subacute cor pulmonale.