Simultaneous choroidal tuberculoma and epididymo-orchitis caused by Mycobacterium tuberculosis.

PURPOSE: To report positive polymerase chain reaction (PCR) for Mycobacterium tuberculosis from the vitreous and epididymal fluid in a patient of choroidal tuberculoma and epididymitis.

DESIGN

Interventional case report.

SETTING

Institutional setting. intervention: Vitreous and epididymal fluid tap subjected to PCR for primer IS 6110 sequence specific for M. tuberculosis. Purification of DNA product and sequencing on an automated DNA sequencer. Institution of antitubercular therapy.

MAIN OUTCOME MEASURE: Matching of sequence with NCBI's data bank response to antitubercular therapy.

RESULTS

DNA products from vitreous and epidiymal fluid matched with IS 6110 sequence of M. tuberculosis. Choroidal granuloma and epididymitis responded to antitubercular therapy.

CONCLUSIONS

Simultaneous choroidal tuberculoma and epididymitis resulted from an infection by M. tuberculosis, and both matched with IS 6110 sequence of M. tuberculosis.