Choroidal tuberculosis diagnosed by polymerase chain reaction. A clinicopathologic case report.

PURPOSE: To show the use of the polymerase chain reaction (PCR) in a granulomatous choroidal lesion to support a diagnosis of tuberculosis.

DESIGN

Observational case report.

TESTING: Nucleic acid target amplification of a choroidal specimen using PCR for detection of Mycobacterium tuberculosis was tested.

MAIN OUTCOME MEASURES: Positive nucleic acid target amplification for M. tuberculosis in the ocular sample was measured.

RESULTS

PCR was positive for M. tuberculosis with appropriate negative controls.

CONCLUSIONS

PCR was thought to be a useful supportive technique in the diagnosis of choroidal tuberculosis.