AJR. American journal of roentgenology · 2009
Residual and recurrent gastrointestinal stromal tumors with KIT mutations: findings at first follow-up CT after imatinib treatment.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Choi Dongil, Yoo Eun Young, Kim Kyoung-Mee, Sohn Tae Sung, Lee Won Jae, Lee Ji Young, Chang Ilsoo
Аннотация
OBJECTIVE: The purpose of this study was to correlate findings on the first follow-up CT after treatment with imatinib in patients with residual or recurrent gastrointestinal stromal tumors (GISTs) with the different types of KIT mutation present at initial resection.
CONCLUSION: Residual and recurrent GISTs with KIT mutation of exon 11 deletion more frequently showed both tumor shrinkage and cystic change on 2-month follow-up CT images after the start of imatinib treatment than did other mutation types.
CONCLUSION: Residual and recurrent GISTs with KIT mutation of exon 11 deletion more frequently showed both tumor shrinkage and cystic change on 2-month follow-up CT images after the start of imatinib treatment than did other mutation types.
Предметные рубрики MeSH
AdultAgedAged, 80 and overBenzamidesFemaleFollow-Up StudiesGastrointestinal Stromal TumorsHumansImatinib MesylateLiver NeoplasmsLung NeoplasmsMaleMiddle AgedMutationNeoplasm Recurrence, LocalNeoplasm SeedingNeoplasm, ResidualPeptide FragmentsPiperazinesProto-Oncogene Proteins c-kitPyrimidinesReceptor, Platelet-Derived Growth Factor alphaRetrospective StudiesSplenic NeoplasmsTomography, X-Ray Computed