Shear wave elastography assessment in the prostate: an intraobserver reproducibility study.

PURPOSE: To assess the intraobserver reproducibility of shear wave elastography (SWE) in the prostate.

MATERIALS AND

METHODS

This study was institutional review board approved with waiver of informed consent. Eighty men (mean age, 66.2±9.2years) with suspected prostate cancer underwent SWE. Young modulus (kPa) was measured at 24 locations in the prostate (superficial and deep locations in paramedian and lateral aspects at the base, mid-gland, and apex levels). The intraobserver reproducibility of two repeated measurements was determined using intraclass correlation coefficients (ICC) and was compared among measurement location, prostate volume, age, and prostate-specific antigen level.

RESULTS

The overall intraobserver reproducibility was excellent (ICC=0.876). In addition, intraobserver reproducibility was excellent for all specified subgroups according to location, prostate volume, and clinical variables (ICC=0.826-0.917). With regard to location, SWE measurements showed substantially higher ICC values in the mid-gland than in the base and apex, in the paramedian prostate than in the lateral prostate, and in superficial locations than in deeper locations. No substantial differences in ICC values were observed according to the prostate volume and clinical variables.

CONCLUSION

Intraobserver reproducibility of SWE measurements in the prostate gland was excellent. There was variability in the intraobserver reproducibility according to location within the prostate, and the operator should be aware of this and take extra caution when performing SWE in these areas.