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Clinical nutrition (Edinburgh, Scotland) · 2025

The GLIM consensus approach to diagnosis of malnutrition: A 5-year update.

СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Cederholm Tommy, Jensen Gordon L, Correia M Isabel T D, Gonzalez M Cristina, Fukushima Ryoji, Pisprasert Veeradej, Blaauw Renee, Braz Diana Cardenas, Carrasco Fernando, Cruz Jentoft Alfonso J, Cuerda Cristina, Evans David C, Fuchs-Tarlovsky Vanessa, Gramlich Leah, Shi Han Ping, Hasse Jeanette M, Hiesmayr Michael, Hiki Naoki, Jager-Wittenaar Harriët, Jahit Shukri, Jáquez Anayanet, Keller Heather, Klek Stanislaw, Malone Ainsley, Mogensen Kris M, Mori Naoharu, Mundi Manpreet, Muscaritoli Maurizio, Ng Doris, Nyulasi Ibolya, Pirlich Matthias, Schneider Stephane, Schueren Marian de van der, Siltharm Soranit, Singer Pierre, Steiber Alison, Tappenden Kelly A, Yu Jianchun, van Gossum André, Wang Jaw-Yuan, Winkler Marion F, Barazzoni Rocco, Compher Charlene

Аннотация

BACKGROUND: The Global Leadership Initiative on Malnutrition (GLIM) introduced an approach for malnutrition diagnosis in 2019 comprised of screening followed by assessment of three phenotypic criteria: weight loss, low BMI, and low muscle mass, and two etiologic criteria: reduced food intake/assimilation, and inflammation/disease burden. This planned update reconsiders the GLIM framework based on published knowledge and experience over the past five years.

METHODS: A GLIM working group (n = 43 members) conducted a literature search spanning 2019-2024 using the keywords "Global Leadership Initiative on Malnutrition or GLIM". Prior GLIM activities providing guidance for use of the criteria on muscle mass and inflammation were reviewed. Successive rounds of review and revision were used to achieve consensus.

RESULTS: More than 400 scientific reports are published in peer-reviewed journals, forming the basis of 10 systematic reviews, some including meta-analyses of GLIM validity that indicate strong construct and predictive validity. Limitations and future priorities are discussed. Working group findings suggest that assessment of low muscle mass should be guided by experience and available technological resources. Clinical judgement may suffice to evaluate the inflammation/disease burden etiologic criterion. No revisions of the weight loss, low BMI, or reduced food intake/assimilation criteria are suggested. Following two rounds of review and revision, the working group secured 100 % agreement with the conclusions reported in the 5-year update.

CONCLUSION: Ongoing initiatives target priorities that include malnutrition risk screening procedures, GLIM adaptation to the intensive care setting, assessment in support of the reduced food intake/assimilation criterion, and determination of malnutrition in obesity.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты