Effect of resting heart rate on coronary collateral formation in patients with chronic total occlusion: resting heart rate and collaterals.

AIM: In this study our aim was to determine the effect of resting heart rate (HR) on the development of coronary collateral circulation (CCC) in patients with chronic total occlusion (CTO).

METHODS

A total of 219 patients who had CTO on their coronary angiography were divided into two groups according to their collateral status. CCC was graded by Rentrop Classification.

RESULTS

Patients with poor collaterals had significantly higher resting HR (79±13.9 vs 74.3±10.5, p=0.005) compared to patients with well collaterals. According to backward logistic regression analyses low HR (OR:0.974, p=0.033), high ejection fraction (OR:1.026, p=0.043) and the presence of CTO at the right coronary artery (OR7colon;3.201, p<0.001) were found to be significantly related with coronary collateral development.

CONCLUSIONS

Increased heart rate was found to be a risk factor for poor collateral formation.