Respiratory Asynchrony and Airway Narrowing in Asthma and Sleep Apnea: A Modeling Approach.

Obstructive Sleep Apnea (OSA) commonly coexists with asthma, yet its influence on airway mechanics remains insufficiently understood. This study explores the relation-ship between oscillometry-based respiratory mechanics and polysomnography (PSG) parameters to gain insights into OSA's impact on airflow dynamics. Short- and long-term breathing variability was assessed using Poincaré plot analysis (SD1/SD2) to evaluate breath-to-breath consistency and airway narrowing. Respiratory cycle features, including peaks and troughs, were extracted to investigate potential associations between PSG-derived metrics and oscillometric measures. The results suggest that these respiratory features provide valuable physiological markers for characterizing airway function and may contribute to future research on the interaction between airway narrowing, sleep apnea, and asthma.