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DOI 10.7507/1001-5515.202211045

Медицинская библиотека · Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2023

[Bionic optic nerve based on perovskite (CsPbBr 3) quantum-dots].

Zeng Pingjun, Jin Xudong, Peng Yubo, Zhao Min, Gao Zhipeng, Li Xiaona, Ji Jianlong, Chen Weiyi

Аннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

The bionic optic nerve can mimic human visual physiology and is a future treatment for visual disorders. Photosynaptic devices could respond to light stimuli and mimic normal optic nerve function. By modifying (Poly(3,4-ethylenedioxythio-phene):poly (styrenesulfonate)) active layers with all-inorganic perovskite quantum dots, with an aqueous solution as the dielectric layer in this paper, we developed a photosynaptic device based on an organic electrochemical transistor (OECT). The optical switching response time of OECT was 3.7 s. To improve the optical response of the device, a 365 nm, 300 mW·cm -2 UV light source was used. Basic synaptic behaviors such as postsynaptic currents (0.225 mA) at a light pulse duration of 4 s and double pulse facilitation at a light pulse duration of 1 s and pulse interval of 1 s were simulated. By changing the way light stimulates, for example, by adjusting the intensity of the light pulses from 180 to 540 mW·cm -2, the duration from 1 to 20 s, and the number of light pulses from 1 to 20, the postsynaptic currents were increased by 0.350 mA, 0.420 mA, and 0.466 mA, respectively. As such, we realized the effective shift from short-term synaptic plasticity (100 s recovery of initial value) to long-term synaptic plasticity (84.3% of 250 s decay maximum). This optical synapse has a high potential for simulating the human optic nerve.

Для цитирования: Zeng Pingjun, Jin Xudong, Peng Yubo, Zhao Min, Gao Zhipeng, Li Xiaona, Ji Jianlong, Chen Weiyi. [Bionic optic nerve based on perovskite (CsPbBr 3) quantum-dots].. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi. 2023. DOI: 10.7507/1001-5515.202211045.

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