Two pyogenic granulomas arising in an epidermoid cyst.

Two pyogenic granulomas arising from the wall of an epidermoid cyst on the midback of a 62-year-old white man are reported. Histologically, each pyogenic granuloma was a polypoid sessile nodule that showed well-vascularized granulation tissue; edema; a mixed inflammatory infiltrate; an epidermal collarette; and a thinned, variably ulcerated epidermis. Although pyogenic granulomas may develop anywhere on the skin, this appears to be the first report of pyogenic granulomas in an epidermoid cyst.