Exploring the Relationship between Parkinson's Disease and Restless Legs Syndrome.

Restless legs syndrome (RLS) frequently coexists with Parkinson's disease (PD), significantly contributing to sleep disturbances and reduced quality of life. This review examines the prevalence, clinical features, pathophysiology, and treatment of RLS in patients with PD. Although prevalence estimates vary due to differences in diagnostic criteria and assessment methods, RLS is consistently linked to a greater burden of nonmotor symptoms, including sleep disruption, depression, and cognitive impairment, which further complicate disease management.