The Role of the Peyronie's Disease Questionnaire in Translation, Cultural Adaptation, and Treatment Management for Portuguese-Speaking Populations.

Peyronie's disease (PD) is characterized by the formation of fibrotic plaques within the penile connective tissue, leading to abnormal curvature, pain, and erectile dysfunction, profoundly affecting patients' physical and psychological well-being. The Peyronie's Disease Questionnaire (PDQ) is a validated instrument designed to assess key aspects of the disease, including pain, sexual function, and psychosocial impact. This narrative review underscores the importance of translating and culturally adapting the PDQ into Portuguese to enhance its applicability for Portuguese-speaking populations. The methodological process includes an analysis of the cultural adaptation of the PDQ and its impact on treatment. Articles from PubMed, Scopus, SciELO, and Google Scholar, published between 2000 and 2024, were reviewed. The study focused on the translation, validation, and cultural adaptation of patient-reported outcome measures (PROMs) for PD. Methodologies such as forward and backward translation, expert panel reviews, and psychometric validation were examined. The findings emphasize the importance of linguistic and cultural validation to improve the use of PROMs in Portuguese-speaking populations and enhance clinical management of the disease. The findings highlight the critical role of the PDQ in clinical management by enabling standardized assessments, personalized care, and optimized therapeutic strategies, ultimately improving outcomes for individuals with PD in diverse cultural settings.