Clinical Outcomes of Femtosecond Laser-Assisted Implantation of Asymmetric ICRS in Keratoconus With No Coincidence of Topographic and Comatic Axes.

PURPOSE: To analyze the clinical outcomes obtained with asymmetric intracorneal corneal ring segments (ICRS) of variable thickness and width in patients with keratoconus, identifying predictive parameters of the final visual outcome.

METHODS

This prospective, longitudinal, non-comparative clinical trial enrolled 35 eyes of 27 patients with keratoconus with a significant difference among corneal topographic and comatic axes. All eyes underwent implantation of AJL-pro+ ICRS (AJL Ophthalmic). Visual, refractive, corneal topographic and aberrometric, and pachymetric changes were evaluated during a 3-month follow-up.

RESULTS

Significant changes were detected at 3 months after surgery in manifest sphere and cylinder, spherical equivalent, overall blur strength, and corrected distance visual acuity (CDVA) (P < .001). No losses of two or more lines of CDVA were observed, whereas 94.3% (33) of eyes gained one or more lines of CDVA. Keratometric readings and the magnitude of anterior corneal astigmatism were significantly reduced with surgery (P < .001), as well as the levels of corneal coma (P < .001) and spherical aberration (P = .007). Likewise, a significant change toward less prolateness was observed (P < .001). Significant correlations were found among the change in CDVA and preoperative CDVA (r = -0.532, P = .001), and between the change in primary coma root mean square and the preoperative level of spherical aberration (r = -0.542, P = .001) and coma root mean square (r = -0.719, P < .001).

CONCLUSIONS

The implantation of the ICRS evaluated in keratoconus with no coincidence between topographic and comatic axes regularizes the corneal shape and reduces the level of higher order aberrations, inducing a significant visual improvement. [J Refract Surg. 2021;37(10):693-699.].