Dermatology (Basel, Switzerland) · 2004
Skin disorders with prominent eosinophilic infiltration treated successfully with nicotine. Report of two cases.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Kanekura Takuro, Usuki Kazunari, Kanzaki Tamotsu
Аннотация
BACKGROUND: Nicotine was effective in the treatment of skin disorders attributable to neutrophils such as pyoderma gangrenosum and orogenital ulcerations due to Behçet's disease.
OBJECTIVE: We assessed the efficacy of nicotine for treating skin disorders with prominent eosinophilic infiltration.
PATIENTS AND METHODS: A 67-year-old man with Kimura's disease was treated for 2 weeks with nicotine chewing gum (6 mg/day). A 50-year-old woman with erythema nodosum with eosinophilic infiltration was treated for 4 weeks with transdermal nicotine patches (5 mg/day).
RESULTS: Both patients showed a dramatic clinical and histopathological improvement.
CONCLUSION: Our results suggest that nicotine may be useful for treating skin disorders with eosinophilic infiltration as well as neutrophilic dermatoses.
OBJECTIVE: We assessed the efficacy of nicotine for treating skin disorders with prominent eosinophilic infiltration.
PATIENTS AND METHODS: A 67-year-old man with Kimura's disease was treated for 2 weeks with nicotine chewing gum (6 mg/day). A 50-year-old woman with erythema nodosum with eosinophilic infiltration was treated for 4 weeks with transdermal nicotine patches (5 mg/day).
RESULTS: Both patients showed a dramatic clinical and histopathological improvement.
CONCLUSION: Our results suggest that nicotine may be useful for treating skin disorders with eosinophilic infiltration as well as neutrophilic dermatoses.