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Internal medicine (Tokyo, Japan) · 2015

HIV-negative Primary Bone Marrow Hodgkin Lymphoma Manifesting with a High Fever Associated with Hemophagocytosis as the Initial Symptom: A Case Report and Review of the Previous Literature.

Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Morita Yasuyoshi, Emoto Masakatsu, Serizawa Kentaro, Rai Shinya, Hirase Chikara, Kanai Yoshitaka, Ohyama Yasuyo, Shiga Toshihiko, Tanaka Hirokazu, Miyatake Junichi, Tatsumi Yoichi, Ashida Takashi, Kimura Masatomo, Ito Masafumi, Matsumura Itaru

Аннотация

A 68-year-old man was referred to our hospital due to a high fever and pancytopenia. Neither tumors nor infectious lesions were detected. Hemophagocytosis was observed on the bone marrow (BM) smear, although without abnormal cells. Prednisolone therapy was ineffective for the patient's high fever. Later on, we obtained the results of a BM biopsy indicating the presence of infiltration of atypical Reed-Sternberg cells, leading to a diagnosis of HIV-negative primary bone marrow Hodgkin lymphoma (PBMHL). However, the patient died of multiple organ failure before receiving chemotherapy. As the clinical course of PBMHL is rapid, physicians must keep in mind its possibility in similar cases.

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