Internal medicine (Tokyo, Japan) · 2023
Aortitis Associated with Prophylactic Short-acting Granulocyte Colony-stimulating Factor Administration: A Case Report and Review of the Literature.
ОбзорКлинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Masuda Yasutaka, Oyama Takashi, Nakazaki Kumi, Nakai Yudai, Sasaki Ken, Matsuda Kensuke, Masamoto Yosuke, Kurokawa Mineo
Аннотация
We herein report an 83-year-old woman with filgrastim-associated aortitis during chemotherapy for relapsed diffuse large B-cell lymphoma. She had been treated with filgrastim as a prophylaxis for neutropenia during the fourth cycle of chemotherapy from day 9 to 18. On day 21, she developed a fever. Contrast-enhanced computed tomography revealed aortitis of the descending aorta. The fever abated with non-steroidal anti-inflammatory drug treatment. A literature review identified a small number of aortitis cases all caused by prophylactic use of granulocyte colony-stimulating factors (G-CSFs), among which short-acting filgrastim was rarely encountered. The present and previous findings imply a possible relationship between aortitis and prophylactic G-CSF usage.