Successful coronary artery bypass grafting after concurrent chemoradiation therapy in a patient with non-small-cell lung cancer: case report and review of the literature.

Mediastinal irradiation has been a major component of the treatment of Hodgkin disease as well as breast and lung tumors. A potentially devastating posttreatment complication of mediastinal irradiation is the development of premature coronary artery disease. Coronary bypass grafting in such patients is difficult because of the presence of extensive radiation-induced mediastinal fibrosis. We present a rare case of patient with non-small-cell lung cancer who underwent successful coronary bypass grafting despite having previously received full-dose thoracic irradiation in conjunction with concurrent chemotherapy.