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DOI 10.2147/ppa.s518080

Медицинская библиотека · Patient preference and adherence · 2025

Psychosocial and Clinical Factors That Differentiate and Predict Patients' Adaptation to Chronic Diseases.

Laza Ruxandra, Al Ghazi Loredana, Lustrea Anca, Lazureanu Voichita Elena, Oancea Cristian Iulian, Luput-Andrica Ioana Melinda, Poplicean Emanuel Ionut, Ilina Razvan, Cireap Natalia, Bob Flaviu, Olariu Nicu, Ionita Ioana, Lazar Sandra, Dehelean Liana, Romosan Radu Stefan, Romosan Ana-Maria

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Аннотация

PURPOSE: Adaptation to chronic disease is an important factor for the quality of life of patients and their families. This research aimed to identify the psychosocial and clinical factors that determine significant differences and best predict the patients' adaptation to chronic diseases. Understanding these factors enables the design of evidence-based preventive interventions that promote early adaptation.

PATIENTS AND

METHODS

A quantitative, non-experimental comparative and predictive study design was conducted. Several clinical, demographic, and psychological factors were measured with an online questionnaire. This study was conducted on a convenience sample of 263 patients with chronic diseases: 63 (24%) had chronic kidney disease with dialysis dependency, 49 (18.6%) had solid neoplasms, 61 (23.2%) had hemopathies, 64 (24.3%) had HIV infection, and 26 (9.9%) had tuberculosis.

RESULTS

Adaptation to chronic disease varies based on the type of diagnosis, with lower adaptation seen in conditions that significantly impact daily life, involve comorbidities, and require frequent treatments, like chronic kidney disease. The most significant predictor of adaptation to the chronic disease is the female gender. Other predictive factors are medication adherence, social support, and self-efficacy in managing chronic disease. Patients without comorbidities and fewer medications are more prone to illness denial, alongside younger, urban, employed, and higher-educated patients, potentially neglecting treatment. Patients with comorbidities and the older patients require greater emotional support, with psychological counseling and support groups being beneficial.

CONCLUSION

Current data underlines the need for an individualized approach to chronic disease management, which should consider demographic and psychological factors in addition to clinical ones. It is important to design early interventions for the development of adaptation to chronic disease, which could include individual and family counseling and education programs for medication administration, treatment at home, adherence to a healthy lifestyle, and inclusion of the patient and his family in social support groups.

Для цитирования: Laza Ruxandra, Al Ghazi Loredana, Lustrea Anca, Lazureanu Voichita Elena, Oancea Cristian Iulian, Luput-Andrica Ioana Melinda, Poplicean Emanuel Ionut, Ilina Razvan, Cireap Natalia, Bob Flaviu, Olariu Nicu, Ionita Ioana, Lazar Sandra, Dehelean Liana, Romosan Radu Stefan, Romosan Ana-Maria. Psychosocial and Clinical Factors That Differentiate and Predict Patients' Adaptation to Chronic Diseases.. Patient preference and adherence. 2025. DOI: 10.2147/ppa.s518080.
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