Медицинская библиотека · International journal of fertility and menopausal studies · 1994

Nuclear presence of two lysosomal enzymes in rat implantation sites.

Duran-Reyes G, Diaz-Flores M, Castillo S, Hicks J J

СтатьяПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

OBJECTIVE

To test the Szego hypothesis of increased beta-glucuronidase and acid phosphatase activities in hormone target tissues.

METHODS

The presence of beta-glucuronidase and acid phosphatase activities in nuclear subcellular fractions obtained from decidual (implantation site) and stromal (nonimplantation zone) tissues was demonstrated by both biochemical measurements and ultramicrographic analysis utilizing a histochemical reaction.

RESULTS

Acid phosphatase was almost twice as abundant in nuclei and lysosomes of epithelial cells (implantation sites), and beta-glucuronidase also was significantly more active in nuclei from epithelial and decidual tissues than in nonimplantation tissue.

CONCLUSION

Our results, utilizing the implantation process as experimental model, support the Szego hypothesis of the lysosomal role in hormonal mechanisms of action.

Для цитирования: Duran-Reyes G, Diaz-Flores M, Castillo S, Hicks J J. Nuclear presence of two lysosomal enzymes in rat implantation sites.. International journal of fertility and menopausal studies. 1994.

Предметные рубрики MeSH

Acid Phosphatase Animals Cell Nucleus Decidua Embryo Implantation Epithelium Female Glucuronidase Histocytochemistry Lysosomes Male Microscopy, Electron Pregnancy Rats Stromal Cells Subcellular Fractions Uterus

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