Paracoccidioidomycosis in Quillabamba, Peru, and its surroundings.

Three cases of paracoccidioidomycosis observed in 1990-1991 in Quillabamba, Peru, and its surroundings are described. The climate and the living conditions of the inhabitants favour paracoccidioidomycosis. It can be assumed that a majority of cases could not be identified, because the symptoms are disguised as other tropical diseases. The application of ketoconazole to the patients showed different results, from optimal to scarce, while temporary remission of the disease was obtained with itraconazole. The best therapy for paracoccidioidomycosis appears to be the application of amphotericin B plus sulphamidics.