American journal of translational research · 2025
Corneal biomechanical properties in myopic anisometropia measured by corneal visualization scheimpflug technology.
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Shao Hui, Zhu Qing, Zhang Lina, Shen Lifang, Zhou Qiuju, Tang Liyan, Meng Yiyu
Аннотация
OBJECTIVE: To explore corneal biomechanical properties in patients with myopic anisometropia using a corneal visualization scheimpflug technology (Corvis ST).
METHODS: We examined 102 eyes from 51 adults with anisometropia (minimum spherical equivalent (SE) of 2.50 D). Patients were classified into two groups based on their SE: high myopia (SE ≥ -6.00 D) (n=52 eyes) and non-high myopia group (SE ≤ -6.00 D) (n=50 eyes). Corneal biomechanical and ocular biometric parameters were measured.
RESULTS: In the high myopia group, axial length (AL), anterior chamber depth (ACD), and central corneal thickness (CCT) were significantly higher compared to the non-high myopia group (all P < 0.001). The second applanation time (A2-time), length of flattened cornea at second applanation (A2-length), and time to highest concavity (HC-time) were shorter in the high myopia group (all P < 0.001). The high myopia group also exhibited lower elasticity and rigidity indices, higher EAI (all P < 0.001), and greater central/mid-peripheral deformation amplitudes (both P < 0.001), with minimal peripheral differences (P=0.074).
CONCLUSION: CorVis ST provides a reliable method for measuring corneal biomechanical properties. In anisometropia, eyes with higher myopia show higher deformation amplitude, faster A2-velocity, shorter A2-time and HC-time, and reduced A2-length.
METHODS: We examined 102 eyes from 51 adults with anisometropia (minimum spherical equivalent (SE) of 2.50 D). Patients were classified into two groups based on their SE: high myopia (SE ≥ -6.00 D) (n=52 eyes) and non-high myopia group (SE ≤ -6.00 D) (n=50 eyes). Corneal biomechanical and ocular biometric parameters were measured.
RESULTS: In the high myopia group, axial length (AL), anterior chamber depth (ACD), and central corneal thickness (CCT) were significantly higher compared to the non-high myopia group (all P < 0.001). The second applanation time (A2-time), length of flattened cornea at second applanation (A2-length), and time to highest concavity (HC-time) were shorter in the high myopia group (all P < 0.001). The high myopia group also exhibited lower elasticity and rigidity indices, higher EAI (all P < 0.001), and greater central/mid-peripheral deformation amplitudes (both P < 0.001), with minimal peripheral differences (P=0.074).
CONCLUSION: CorVis ST provides a reliable method for measuring corneal biomechanical properties. In anisometropia, eyes with higher myopia show higher deformation amplitude, faster A2-velocity, shorter A2-time and HC-time, and reduced A2-length.