Assessment of preload and fluid responsiveness in intensive care unit. How good are we?

Early recognition and treatment of acute circulatory failure and tissue hypoperfusion are paramount for improving the odds of survival in critically ill patients. Fluid volume resuscitation is the mainstay intervention in redistributive and hypovolemic shock. Correct identification of a patient who would benefit from fluid administration allows optimization of hemodynamics and avoids ineffective or even deleterious volume expansion that may result in worsening of gas exchange and pulmonary edema in fluid unresponsive patients, in whom inotropic and/or vasopressor support should preferentially be used. The use of dynamic changes in central venous pressure, pulse pressure, and echocardiography for assessment of inferior vena cava diameter variations during respiration allows prediction of fluid volume responsiveness in hemodynamically unstable patients. The use of these bedside approaches and passive leg raising maneuver, which is a reversible and quick fluid volume challenge, allows timely formulation of treatment strategy in patients with shock.