Critical appraisal of ophthalmic ketorolac in treatment of pain and inflammation following cataract surgery.

BACKGROUND

The purpose of this review was to provide a critical appraisal of the literature supporting the efficacy of ophthalmic ketorolac (Acuvail(®)) in the treatment of pain and inflammation after cataract surgery.

METHODS

Literature search and expert opinion of the authors.

RESULTS

Recent studies indicate greater intraocular drug levels in the anterior chamber and iris-ciliary body after topical application of Acuvail in comparison with older formulations of ketorolac. A large randomized, multicenter, placebo-controlled study demonstrated significantly less inflammation and pain after cataract surgery using Acuvail.

CONCLUSION

Acuvail appears to be effective in reducing post-cataract surgery pain and inflammation.