Uncharted Territory: The First Case of Cardiac Myxoma in a Patient With NF2.

BACKGROUND

Cardiac myxoma is a benign tumor, typically originating in the left atrium, and is often linked to Carney complex. In our literature review, there are no case reports of cardiac myxoma in patients with neurofibromatosis type 2 (NF2).

CASE SUMMARY: A 60-year-old man presented with dizziness and was found to have meningioma and vestibular schwannoma, consistent with NF2. Cardiac myxoma was incidentally diagnosed through echocardiography and confirmed by cardiac magnetic resonance imaging and tissue pathology. The mass was surgically resected. The patient was offered genetic testing; however, he decided to not undergo further testing.

DISCUSSION: NF2 is an inherited autosomal dominant disorder associated with vestibular schwannoma, meningioma, ependymoma, cataract, lenticular opacities, and retinal hamartomas.

TAKE-HOME MESSAGE: Further research is needed to investigate the potential risk of cardiac myxoma in patients with NF2 and the benefit of routine screening for myxomas in this population.