MedElevator
Войти в исследования Revista medica del Instituto Mexicano del Seguro Social · 2019
[Long-term efficacy of parathyroidectomy in secondary and tertiary hyperparathyroidism].
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
González-Cantú Arnulfo, Romero-Ibarguengoitia María Elena, Quintanilla-Flores Dania Lizet, Reza-Albarrán Alfredo, Herrera-Hernández Miguel, Pantoja-Millán Juan Pablo, Sierra-Salazar Mauricio, Velázquez-Fernández David, Gómez-Pérez Francisco Javier
Аннотация
BACKGROUND: Secondary and tertiary hyperparathyroidism (SHPT and THPT), are complications of chronic kidney disease (CKD), characterized by high levels of serum parathormone, hyperphosphatemia or hypercalcemia, respectively. If diet and pharmacological therapies fail, clinical practice guidelines suggest parathyroidectomy (PTX). Some studies have described its effectiveness and safety, but these have not included Mexican population.
OBJECTIVE: To describe long-term effectiveness of PTX in Mexican patients with SHPT or THPT.
MATERIAL AND METHODS: Observational and retrospective study of patients treated with PTX between 1995 and 2014 in a third level hospital in Mexico City. The analyses included the follow-up of medical treatment and biochemical assessment every three months during the first year, and the last evaluation. Permutation and chi square tests were used.
RESULTS: The study included 27 patients (14 women). The follow-up mean was 39 months; 61.5% had SHPT. All biochemical parameters, except magnesium, were reduced in the first year of follow-up. In the long term, SHPT was controlled in 80% using PTH under a 300 pg/mL criterion, and 90% in patients with THPT using calcium criterion. Persistent hypocalcemia was present in 11.5% of cases.
CONCLUSION: Mexican patients with SHPT and THPT could be successfully treated with surgery with low risk of hypocalcemia.
OBJECTIVE: To describe long-term effectiveness of PTX in Mexican patients with SHPT or THPT.
MATERIAL AND METHODS: Observational and retrospective study of patients treated with PTX between 1995 and 2014 in a third level hospital in Mexico City. The analyses included the follow-up of medical treatment and biochemical assessment every three months during the first year, and the last evaluation. Permutation and chi square tests were used.
RESULTS: The study included 27 patients (14 women). The follow-up mean was 39 months; 61.5% had SHPT. All biochemical parameters, except magnesium, were reduced in the first year of follow-up. In the long term, SHPT was controlled in 80% using PTH under a 300 pg/mL criterion, and 90% in patients with THPT using calcium criterion. Persistent hypocalcemia was present in 11.5% of cases.
CONCLUSION: Mexican patients with SHPT and THPT could be successfully treated with surgery with low risk of hypocalcemia.