Some clinical observations on acne vulgaris.

The clinical similarties between the cutaneous manifestations, specially, the heper-kerototic follicular papules of hypoyitaminosis and those of Darier's disease and pity riasis, rubra pilaris, provide the rationale for the first testing Vitamin-A, as a therapy for skin diseases.Table I shows the trials taken on 125 patients, which attended our clinic, suffering from Acene, Plaques of Psoriasis Vulgaris, Psoriati arthritis and Keratinisation. These trials are taken at three different medical centres and results so obtained are recorded in this paper.