Corneal ulceration and perforation with ketorolac tromethamine (Acular) use after PRK.

PURPOSE: To report a case of corneal ulceration and perforation after PRK connected with high doses of ketorolac tromethamine (Acula).

METHODS

A 31-year-old man presented 5 days after PRK in the left eye with corneal ulceration and perforation requiring penetrating keratoplasty. The patient admitted to using Acular every hour, ciprofloxocin every hour, and prednisolone acetate 1% QID postoperatively.

RESULTS

Laboratory tests, including corneal cultures, were normal. A diagnosis of corneal ulceration secondary to incorrect use of high-dose ketorolac tromethamine was made.

CONCLUSION

Judicious patient counseling is recommended when using topical NSAIDs in the setting of PRK.