Research-led innovation for integrated tick management and acaricide resistance mitigation in livestock.

Ticks and tick-borne diseases represent a major threat to livestock health and productivity, particularly in (sub)tropical regions. Chemical acaricides remain the main control method, but repeated use has driven resistance and raised concerns about food safety, welfare, and environmental impact. Limited development of new ectoparasiticides has left farmers dependent on outdated options. Integrated tick management offers a sustainable approach by combining acaricides with biological controls, vaccines, resistant breeds, and improved husbandry. However, adoption is hindered by the availability, accessibility, and acceptance of current alternatives, as well as by the lack of innovative solutions. Key priorities include resistance monitoring, improving stewardship, and promoting farmer-led solutions. Long-term success will require aligning innovations with local needs, building trust, and fostering collaboration across public, private, and communities.