Understanding Glaucoma: Why it Remains a Leading Cause of Blindness Worldwide.

Glaucoma is one of the leading causes of irreversible blindness worldwide and is often referred to as the "silent thief of sight", because it often progresses without noticeable symptoms until significant vision loss occurs. With an estimated 76 million patients affected in 2020 and a forecast of over 111 million by 2040, the global situation requires urgent attention. Vision loss caused by glaucoma is irreversible but largely preventable, highlighting the importance of early detection and treatment. Diagnosis presents significant challenges, particularly due to the asymptomatic nature of the disease and age-related risk factors. Inequalities in care and access to appropriate treatments are other barriers leading to delayed diagnoses. Early diagnosis and interventions are critical to slow disease progression, protect remaining vision and improve the quality of life of those affected. These measures are particularly important to minimise the psychological impact and impairment in daily activities. The use of innovative technologies and targeted interventions could help improve the early detection and treatment of glaucoma and thus reduce the risk of irreversible vision loss.