Treatment of Viral Infections During Pregnancy: Part 1: Herpes Simplex Virus and Cytomegalovirus.

Viral infections are common in pregnancy and contribute significantly to maternal and fetal/neonatal morbidity and mortality. Certain viruses cause congenital infection with potentially devastating fetal/neonatal consequences, ranging from structural anomalies (birth defects), fetal growth restriction, and stillbirth to congenital viral syndromes with long-term end-organ damage and neurodevelopmental disorders. While a comprehensive review of all viral infections in pregnancy is beyond the scope of this article, this review focuses on the management of herpes simplex virus and cytomegalovirus.