Journal of the American Medical Directors Association · 2026
Longitudinal Changes in Long COVID Symptoms by Sex and Age Among Geriatric Residents of Residential Care Facilities: A Multicenter Cohort Study in Hefei, China.
СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Wu Qiqin, Zhao Yuqing, Fang Xin, Chen Tong, Zhang Chengyuan, Liu Zhengkui, Wang Cui
Аннотация
OBJECTIVES: This study aimed to investigate the symptomatic evolution of long COVID and to identify factors influencing its progression in a predominantly older population.
DESIGN: This was a prospective cohort study with long-term follow-up, conducting 3 assessment waves between January 8, 2023, and August 15, 2024.
SETTING AND PARTICIPANTS: The study included 228 of an initial cluster sample of 266 residents from 5 long-term care facilities in Hefei, China, all with prior SARS-CoV-2 infection, who completed all follow-ups.
METHODS: Data were collected via study-specific demographic questionnaires and a long COVID symptom scale. Descriptive statistics, Cochran's Q tests, t tests, partial correlations controlling for age, and generalized estimating equations were used to analyze symptom distribution, comparisons, longitudinal relationships, and influencing factors.
RESULTS: At T1, low mood (81.1%) and sleep disturbances (81.1%) were the most common symptoms. At T2, fatigue (54.8%) and pain in other body parts (59.2%) became the main symptoms. Dizziness (44.7%) was the most frequent symptom at T3. Independent samples t tests revealed that women had consistently higher total symptom scores than men (P < .05). Compared with the younger group (<76 years), the older group (≥76 years) had higher scores at T2 across multiple symptoms and in the overall score. Partial correlation analysis showed the correlation was strongest between T1 and T2 (r = 0.224, P = .001). The generalized estimating equations model indicated that men had a lower risk of symptoms in most organ systems (OR = 0.257-0.912).
CONCLUSIONS AND IMPLICATIONS: Long COVID symptoms in predominantly older individuals showed progressive improvement. Women had more severe symptoms and advanced age slowed the recovery process. However, long-term recovery depended on the individual. This study advocates for implementing personalized, stage-specific care models over standardized protocols in residential care facilities, emphasizing the need for targeted monitoring of high-risk subgroups such as women and older residents.
DESIGN: This was a prospective cohort study with long-term follow-up, conducting 3 assessment waves between January 8, 2023, and August 15, 2024.
SETTING AND PARTICIPANTS: The study included 228 of an initial cluster sample of 266 residents from 5 long-term care facilities in Hefei, China, all with prior SARS-CoV-2 infection, who completed all follow-ups.
METHODS: Data were collected via study-specific demographic questionnaires and a long COVID symptom scale. Descriptive statistics, Cochran's Q tests, t tests, partial correlations controlling for age, and generalized estimating equations were used to analyze symptom distribution, comparisons, longitudinal relationships, and influencing factors.
RESULTS: At T1, low mood (81.1%) and sleep disturbances (81.1%) were the most common symptoms. At T2, fatigue (54.8%) and pain in other body parts (59.2%) became the main symptoms. Dizziness (44.7%) was the most frequent symptom at T3. Independent samples t tests revealed that women had consistently higher total symptom scores than men (P < .05). Compared with the younger group (<76 years), the older group (≥76 years) had higher scores at T2 across multiple symptoms and in the overall score. Partial correlation analysis showed the correlation was strongest between T1 and T2 (r = 0.224, P = .001). The generalized estimating equations model indicated that men had a lower risk of symptoms in most organ systems (OR = 0.257-0.912).
CONCLUSIONS AND IMPLICATIONS: Long COVID symptoms in predominantly older individuals showed progressive improvement. Women had more severe symptoms and advanced age slowed the recovery process. However, long-term recovery depended on the individual. This study advocates for implementing personalized, stage-specific care models over standardized protocols in residential care facilities, emphasizing the need for targeted monitoring of high-risk subgroups such as women and older residents.