Boletin medico del Hospital Infantil de Mexico · 2023
Hyperferritinemic sepsis secondary to invasive Toxoplasma gondii in a child with untreated HIV.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Domínguez-Rojas Jesús, Caute-Lara Jackeline, Caqui-Vilca Patrick, Cruz-Arpi Mario, Martel-Ramírez Carlos, Quispe-Chipana Miguel, Sánchez-Rodríguez Abel, Atamari-Anahui Noé
Аннотация
BACKGROUND: Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis.
CASE REPORT: We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution.
CONCLUSIONS: The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications.
CASE REPORT: We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution.
CONCLUSIONS: The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications.