[Evaluation of an automated system of measuring erythrocyte aggregation in dysglobulinemia treated by plasma exchange].

Characteristics of a new erythrocyte aggregameter were evaluated in 7 patients with monoclonal dysglobulinemia (5 multiple myeloma, 1 Waldenström disease, 1 CLL with monoclonal immunoglobulin) treated by plasma exchange. This apparatus measures modifications of light retro-diffused by erythrocytes suspension after shear arrest. All parameters measured: Ta, Tf, S10, gamma D, gamma S were modified after plasma exchange: either immediately after the first or after the second or third plasma exchange. These findings demonstrate the value of this new technique for evaluating red cell aggregation. These data should be completed by rheological assessment of dysglobulinemia treated by plasma exchange.