Gastrointestinal endoscopy · 2008
Endoscopic submucosal dissection of recurrent or residual superficial esophageal cancer after chemoradiotherapy.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Saito Yutaka, Takisawa Hajime, Suzuki Haruhisa, Takizawa Kouhei, Yokoi Chizu, Nonaka Satoru, Matsuda Takahisa, Nakanishi Yukihiro, Kato Ken
Аннотация
BACKGROUND: Treatment of local recurrent or residual superficial esophageal squamous-cell carcinoma (SCC) with conventional EMR often results in a piecemeal resection that requires further intervention.
OBJECTIVE: The aim of this study was to evaluate the efficacy of endoscopic submucosal dissection (ESD).
DESIGN: A case series.
PATIENTS: Between January 2006 and September 2006, 4 local recurrent or residual superficial esophageal SCCs were treated by ESD.
INTERVENTIONS: ESD procedures were performed by using a bipolar needle knife and an insulation-tipped knife. After injection of glycerol into the submucosal (sm) layer, a circumferential incision was made, and an sm dissection was performed. All lesions were determined to be intramucosal or sm superficial, without lymph-node metastasis by EUS before treatment.
MAIN OUTCOME MEASUREMENTS: Tumor size, en bloc resection rate, tumor-free lateral margin rates, and complications were recorded.
RESULTS: All 4 ESD cases were successfully resected en bloc, and the tumor-free lateral margin rate was 75% (3/4) by histopathology examination. The mean tumor size of the resected specimens was 35 mm (range, 15-50 mm). There were no complications.
LIMITATIONS: The number of ESDs in our series was limited, and there are no long-term follow-up data.
CONCLUSIONS: ESD for recurrent or residual superficial esophageal tumors after chemoradiotherapy achieves the goal of an en bloc resection, with a low rate of incomplete treatment without any greater risk than the EMR technique.
OBJECTIVE: The aim of this study was to evaluate the efficacy of endoscopic submucosal dissection (ESD).
DESIGN: A case series.
PATIENTS: Between January 2006 and September 2006, 4 local recurrent or residual superficial esophageal SCCs were treated by ESD.
INTERVENTIONS: ESD procedures were performed by using a bipolar needle knife and an insulation-tipped knife. After injection of glycerol into the submucosal (sm) layer, a circumferential incision was made, and an sm dissection was performed. All lesions were determined to be intramucosal or sm superficial, without lymph-node metastasis by EUS before treatment.
MAIN OUTCOME MEASUREMENTS: Tumor size, en bloc resection rate, tumor-free lateral margin rates, and complications were recorded.
RESULTS: All 4 ESD cases were successfully resected en bloc, and the tumor-free lateral margin rate was 75% (3/4) by histopathology examination. The mean tumor size of the resected specimens was 35 mm (range, 15-50 mm). There were no complications.
LIMITATIONS: The number of ESDs in our series was limited, and there are no long-term follow-up data.
CONCLUSIONS: ESD for recurrent or residual superficial esophageal tumors after chemoradiotherapy achieves the goal of an en bloc resection, with a low rate of incomplete treatment without any greater risk than the EMR technique.