Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
Prevalence and Risk Factors of Pediatric Delirium in Critically Ill Children: A Study Using Cornell Assessment of Pediatric Delirium Tool at a Tertiary Care Hospital.
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Nashit Muhammad, Haque Anwar Ul, Mirza Sadiq, Habib Irfan, Shahid Saba, Ahmed Abdul Rahim, Jurair Humaira
Аннотация
BACKGROUND AND AIMS: The Cornell Assessment of Pediatric Delirium (CAPD)-revised is a validated tool for detecting delirium in critically ill children. This study aimed to determine the prevalence of delirium and associated risk factors in a pediatric intensive care population using CAPD.
MATERIALS AND METHODS: A descriptive cross-sectional study was conducted among 201 critically ill children aged 1 month-14 years admitted to a tertiary care hospital in Karachi, Pakistan, from August 2021 to February 2022. Delirium was assessed twice daily for three consecutive days using CAPD. A score of ≥9 was considered diagnostic.
RESULTS: Delirium was identified in 24.9% of patients (n = 50/201). The mean age was 5.14 ± 4.03 years, with 61.7% male (n = 124/201). Significant risk factors included comorbidities (n = 34/201, OR = 3.45, 95% CI: 1.78-6.70, p = 0.0005), developmental delay (n = 3/201, OR = 5.12, 95% CI: 1.34-19.54, p = 0.015), benzodiazepine use (n = 45/201, OR = 2.89, 95% CI: 1.52-5.50, p = 0.001), antiepileptic use (n = 38/201, OR = 2.67, 95% CI: 1.38-5.17, p = 0.004), high-flow oxygen (n = 60/201, OR = 2.31, 95% CI: 1.20-4.45, p = 0.012), and mechanical ventilation (n = 55/201, OR = 3.12, 95% CI: 1.62-6.01, p = 0.001).
CONCLUSION: Delirium affected nearly one-quarter of critically ill children, with comorbidities, developmental delay, use of sedatives, and advanced respiratory as key risk factors. Cornell Assessment of Pediatric Delirium is a valuable tool for routine screening to enable early recognition and management of pediatric delirium. More multicenter studies are recommended for further validation.
HOW TO CITE THIS ARTICLE: Nashit M, Ul Haque A, Mirza S, Habib I, Shahid S, Ahmed AR, et al. Prevalence and Risk Factors of Pediatric Delirium in Critically Ill Children: A Study Using Cornell Assessment of Pediatric Delirium Tool at a Tertiary Care Hospital. Indian J Crit Care Med 2025;29(9):760-764.
MATERIALS AND METHODS: A descriptive cross-sectional study was conducted among 201 critically ill children aged 1 month-14 years admitted to a tertiary care hospital in Karachi, Pakistan, from August 2021 to February 2022. Delirium was assessed twice daily for three consecutive days using CAPD. A score of ≥9 was considered diagnostic.
RESULTS: Delirium was identified in 24.9% of patients (n = 50/201). The mean age was 5.14 ± 4.03 years, with 61.7% male (n = 124/201). Significant risk factors included comorbidities (n = 34/201, OR = 3.45, 95% CI: 1.78-6.70, p = 0.0005), developmental delay (n = 3/201, OR = 5.12, 95% CI: 1.34-19.54, p = 0.015), benzodiazepine use (n = 45/201, OR = 2.89, 95% CI: 1.52-5.50, p = 0.001), antiepileptic use (n = 38/201, OR = 2.67, 95% CI: 1.38-5.17, p = 0.004), high-flow oxygen (n = 60/201, OR = 2.31, 95% CI: 1.20-4.45, p = 0.012), and mechanical ventilation (n = 55/201, OR = 3.12, 95% CI: 1.62-6.01, p = 0.001).
CONCLUSION: Delirium affected nearly one-quarter of critically ill children, with comorbidities, developmental delay, use of sedatives, and advanced respiratory as key risk factors. Cornell Assessment of Pediatric Delirium is a valuable tool for routine screening to enable early recognition and management of pediatric delirium. More multicenter studies are recommended for further validation.
HOW TO CITE THIS ARTICLE: Nashit M, Ul Haque A, Mirza S, Habib I, Shahid S, Ahmed AR, et al. Prevalence and Risk Factors of Pediatric Delirium in Critically Ill Children: A Study Using Cornell Assessment of Pediatric Delirium Tool at a Tertiary Care Hospital. Indian J Crit Care Med 2025;29(9):760-764.