[The determination in the polyclinic of the genetic risk for the development of chronic cholecystitis].

Studies into the genealogical anamnesis and a number of genetic characteristics of patients with chronic cholecystitis allowed one to confirm the significance of hereditary burden in the development of cholecystitis and to identify genetic markers (B(III) blood group), type Hp 1-1, HLA A3, HLA A30 and HLA B5, as well genetic protectors (O(I) blood group), HLA B8, HLA B14 of the disease. It has been established that hereditary factors play the most important role in the development of chronic calculous cholecystitis as compared to acalculous cholecystitis, which manifests itself in greater significance of hereditary burden and greater power of association with genetic markers of the disease.