Impact of Hearing-Targeted and Universal Newborn Screening on the Observed Birth Prevalence of Congenital Cytomegalovirus Infection.

This retrospective study estimated the birth prevalence of congenital cytomegalovirus (cCMV) in southeastern Minnesota, US. The birth prevalence was about 3 times and about 18 times greater following implementation of hearing-targeted and universal newborn cCMV screening, respectively. Most infants born with cCMV will not be identified in the absence of systematic newborn screening programs.