Journal of refractive surgery (Thorofare, N.J. : 1995) · 2025
Anterior Segment Characteristics Changes After Implantable Collamer Lens V4c in Low Anterior Chamber Depth Eyes: An Optical Coherence Tomography Study.
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Su Zhanyu, Wang Shanshan, Li Siya, Wang Ruiwen, Li Yaxin, Di Shuli, Xu Yaqian, Hu Jinwei, Ortega-Usobiaga Julio, Wang Zheng, Wang Ming X, Li Kangjun
Аннотация
PURPOSE: To investigate anterior segment changes after implantable collamer lens V4c (ICL-V4c; STAAR Surgical) implantation in eyes with low anterior chamber depth (ACD) and compare them with eyes with normal ACD.
METHODS: This prospective, interventional case-control study included 96 eyes of 48 patients with a low ACD (< 2.8 mm) and 44 eyes of 22 patients with normal ACD (≥ 2.8 mm) receiving a 12.1-mm ICL. All patients underwent follow-up and comprehensive ophthalmic examinations preoperatively and at 1, 3, and 6 months after surgery. Anterior segment parameters, including ACD, anterior chamber width, crystalline lens rise, anterior chamber angle, trabecular-iris angle (TIA), angle opening distance, trabecular-iris space area, the distance from cornea to ICL, and vault were all conducted by optical coherence tomography. These parameters from the last follow-up (6 months postoperatively) were used for statistical analysis to assess changes in anterior segment structure and their relationship with vault height.
RESULTS: The mean safety and efficacy index in eyes with low ACD were 1.23 ± 0.22 and 1.21 ± 0.08 respectively. In both groups, anterior chamber structure parameters become narrower compared to preoperatively (all P < .05). Preoperative ACD and C-ICL demonstrated significant correlations with ICL vault in eyes with low ACD (P < .001). Compared with eyes with normal ACD preoperatively, eyes with low ACD are more prone to have low vault (P < .01). There is a correlation between normal vault and corneal horizontal white-to-white distance (P = .032), ACD (P = .046), and temporal TIA500 (P = .016).
CONCLUSIONS: ICL-V4c surgery in eyes with low ACD is safe and efficacious. In patients with low ACD, the normal vault could be better anticipated by considering preoperative anterior chamber angle, white-to-white distance, and ACD. [J Refract Surg. 2025;41(4):e342-e355.].
METHODS: This prospective, interventional case-control study included 96 eyes of 48 patients with a low ACD (< 2.8 mm) and 44 eyes of 22 patients with normal ACD (≥ 2.8 mm) receiving a 12.1-mm ICL. All patients underwent follow-up and comprehensive ophthalmic examinations preoperatively and at 1, 3, and 6 months after surgery. Anterior segment parameters, including ACD, anterior chamber width, crystalline lens rise, anterior chamber angle, trabecular-iris angle (TIA), angle opening distance, trabecular-iris space area, the distance from cornea to ICL, and vault were all conducted by optical coherence tomography. These parameters from the last follow-up (6 months postoperatively) were used for statistical analysis to assess changes in anterior segment structure and their relationship with vault height.
RESULTS: The mean safety and efficacy index in eyes with low ACD were 1.23 ± 0.22 and 1.21 ± 0.08 respectively. In both groups, anterior chamber structure parameters become narrower compared to preoperatively (all P < .05). Preoperative ACD and C-ICL demonstrated significant correlations with ICL vault in eyes with low ACD (P < .001). Compared with eyes with normal ACD preoperatively, eyes with low ACD are more prone to have low vault (P < .01). There is a correlation between normal vault and corneal horizontal white-to-white distance (P = .032), ACD (P = .046), and temporal TIA500 (P = .016).
CONCLUSIONS: ICL-V4c surgery in eyes with low ACD is safe and efficacious. In patients with low ACD, the normal vault could be better anticipated by considering preoperative anterior chamber angle, white-to-white distance, and ACD. [J Refract Surg. 2025;41(4):e342-e355.].