Retinal cases & brief reports · 2009
Multicentric castleman disease with ocular involvement: a clinicopathologic case report.
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Emerson Geoffrey G, Lim Lyndell, Loriaux Marc, Yassin Hazem M, Flaxel Christina J, Smith Justine R, Wilson David J
Аннотация
PURPOSE: To describe an ocular manifestation of Castleman disease, a rare lymphoproliferative disorder characterized by sheets of abundant plasma cells in the interfollicular spaces of lymph nodes, most commonly in the abdomen, mediastinum, and cervical chain.
METHODS: Clinicopathologic case report.
PATIENT: A 69-year-old man with lymphadenopathy and bilateral choroidal infiltrates.
RESULTS: Initially, we suspected systemic lymphoma with ocular involvement. Lymph node biopsy revealed Castleman disease without a monoclonal component. Choroidal biopsy showed lymphocytic and plasma cell infiltration.
CONCLUSION: To our knowledge, this is the first clinicopathologic report of multicentric Castleman disease involving the eye.
METHODS: Clinicopathologic case report.
PATIENT: A 69-year-old man with lymphadenopathy and bilateral choroidal infiltrates.
RESULTS: Initially, we suspected systemic lymphoma with ocular involvement. Lymph node biopsy revealed Castleman disease without a monoclonal component. Choroidal biopsy showed lymphocytic and plasma cell infiltration.
CONCLUSION: To our knowledge, this is the first clinicopathologic report of multicentric Castleman disease involving the eye.