Journal of cardiology cases · 2025
A rare case of cytomegalovirus myocarditis complicating rejection after heart transplantation: Case report and review of literature.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Abete Raffaele, Iacovoni Attilio, Vittori Claudia, Sebastiani Roberta, Candiago Elisabetta, Gianatti Andrea, Terzi Amedeo, Senni Michele
Аннотация
UNLABELLED: A 49-year-old female with terminal hypertrophic cardiomyopathy underwent orthotopic heart transplantation. The patient developed early acute rejection. Intensifying therapy led to improvement, but cytomegalovirus (CMV) myocarditis emerged. Aggressive management, including high-dose ganciclovir and intravenous immunoglobulin, resulted in negativization of CMV and rejection markers. Cardiac function recovered, emphasizing the challenges and successful multidisciplinary approach in managing complex post-transplant complications.
LEARNING OBJECTIVES: To diagnose and treat complications in heart transplantation, such as opportunistic infections and cellular and/or antibody-mediated rejection. To underline role of endomyocardial biopsy in heart transplant monitoring.
LEARNING OBJECTIVES: To diagnose and treat complications in heart transplantation, such as opportunistic infections and cellular and/or antibody-mediated rejection. To underline role of endomyocardial biopsy in heart transplant monitoring.