The occurrence of hyaline cytoplasmic inclusions in the nerve cells of the hypoglossal nucleus in human autopsy material.

Among 440 adults (ranging in age from 41 to 99 years) who were examined for hyaline cytoplasmic inclusions (HCI) within cells of the hypoglossal nuclei of the medulla oblongata, HCI were found in 75 (17.0%). No definite correlation was noted between HCI and specific diseases. The morphological and histochemical descriptions and pathological interpretation as well as frequency of HCI as reported in the literature were reviewed. There was no evidence that the presence of HCI was related to a specific disease, ages or sex.