Molecular biology reports · 2021
sST2 and Galectin-3 genotyping in patients with persistent atrial fibrillation.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Saez-Maleta Ruth, Merino-Merino Ana, Gundin-Menendez Simon, Salgado-Aranda Ricardo, AlKassam-Martinez Daniel, Pascual-Tejerina Virginia, Martin-Gonzalez Javier, Garcia-Fernandez Javier, Perez-Rivera Jose-Angel
Аннотация
Genotyping of ST2 and galectin-3 in atrial fibrillation (AF) is not well analyzed. The aim of our study was to analyze the possible relationship between levels of sST2 and galectin-3 and three polymorphisms in patients with AF. We included 125 patients with persistent AF undergoing electric cardioversion. We analyzed sST2 and galectin-3 levels and three polymorphisms in peripheral blood samples. Rs2274273 was significantly related with levels of galectin-3. Rs1558648 was associated with levels of sST2 but rs13019803 were not. None of the polymorphisms were connected to the variation of biomarkers levels during the follow up. We found a relationship between rs2274273 and galectin-3 levels and rs1558648 and sST2 levels in patients with AF.