Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation · 2009
Therapeutic failure in a renal transplant patient with Pneumocystis jiroveci pneumonia: a case report.
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Archontoulis Nikolaos K, Staikou Chryssoula V
Аннотация
OBJECTIVES: Pneumocystis jiroveci pneumonia is common in immunocompromised individuals.
PATIENTS: This case report describes an immunosuppressed patient who acquired P jiroveci pneumonia 6 months after renal transplant surgery.
RESULTS: The patient experienced many pneumonia-related complications and adverse effects from drug therapy, and despite treatment with various antibiotic agents, he died on the 62nd day after his admission to the intensive care unit.
CONCLUSIONS: The therapeutic failure of the drug of choice (co-trimoxazole) was evident. This case raises questions about the development of P jiroveci resistance to current therapies.
PATIENTS: This case report describes an immunosuppressed patient who acquired P jiroveci pneumonia 6 months after renal transplant surgery.
RESULTS: The patient experienced many pneumonia-related complications and adverse effects from drug therapy, and despite treatment with various antibiotic agents, he died on the 62nd day after his admission to the intensive care unit.
CONCLUSIONS: The therapeutic failure of the drug of choice (co-trimoxazole) was evident. This case raises questions about the development of P jiroveci resistance to current therapies.