Journal of cataract and refractive surgery · 2011
Posterior capsule opacification in eyes with steroid-induced cataracts: Comparison of early results.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Praveen Mamidipudi R, Shah Gauri D, Vasavada Abhay R, Shah Alpesh R, Johar Kaid, Gami Yogesh, Diwan Rasesh P, Shah Shubhangi M
Аннотация
PURPOSE: To evaluate posterior capsule opacification (PCO) development after cataract surgery in eyes with or without a history of steroid use.
SETTING: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.
DESIGN: Comparative case series.
METHODS: This study comprised consecutive patients with a history of steroid intake (oral, inhaled, injectable, or topical) for at least 4 months who developed posterior subcapsular cataract (PSC) (study group) and patients without a history of steroid intake with uncomplicated PSC (control group). Standardized surgery was performed in both groups. Digital retroillumination photographic documentation was performed 1 month and 1 year postoperatively. The digital images were analyzed for PCO using Evaluation of Posterior Capsule Opacification (EPCO) software; the entire intraocular lens (IOL) optic and the central 3.0 mm optic area were evaluated. The EPCO score and EPCO area were determined.
RESULTS: One year postoperatively, the mean EPCO score was statistically significantly higher in the study group (n = 30) than in the control group (n = 60) (0.33 ± 0.37 [SD] versus 0.15 ± 0.26), as was the mean EPCO area (0.323 ± 0.36 versus 0.15 ± 0.26) (both P<.04). Within the central 3.0 mm optic area, the mean EPCO scores (0.149 ± 0.309 versus 0.003 ± 0.016 P<.04) and mean EPCO area values (0.149 ± 0.309 versus 0.003 ± 0.016) were statistically significantly higher in the study group (P<.04).
CONCLUSION: Steroid-induced PSC was associated with a higher risk for PCO after cataract surgery at the 1-year follow-up.
FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.
SETTING: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.
DESIGN: Comparative case series.
METHODS: This study comprised consecutive patients with a history of steroid intake (oral, inhaled, injectable, or topical) for at least 4 months who developed posterior subcapsular cataract (PSC) (study group) and patients without a history of steroid intake with uncomplicated PSC (control group). Standardized surgery was performed in both groups. Digital retroillumination photographic documentation was performed 1 month and 1 year postoperatively. The digital images were analyzed for PCO using Evaluation of Posterior Capsule Opacification (EPCO) software; the entire intraocular lens (IOL) optic and the central 3.0 mm optic area were evaluated. The EPCO score and EPCO area were determined.
RESULTS: One year postoperatively, the mean EPCO score was statistically significantly higher in the study group (n = 30) than in the control group (n = 60) (0.33 ± 0.37 [SD] versus 0.15 ± 0.26), as was the mean EPCO area (0.323 ± 0.36 versus 0.15 ± 0.26) (both P<.04). Within the central 3.0 mm optic area, the mean EPCO scores (0.149 ± 0.309 versus 0.003 ± 0.016 P<.04) and mean EPCO area values (0.149 ± 0.309 versus 0.003 ± 0.016) were statistically significantly higher in the study group (P<.04).
CONCLUSION: Steroid-induced PSC was associated with a higher risk for PCO after cataract surgery at the 1-year follow-up.
FINANCIAL DISCLOSURE: No author has a financial or proprietary interest in any material or method mentioned.