The Journal of experimental medicine · 2021
Inhibition of ADAM17 impairs endothelial cell necroptosis and blocks metastasis.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Bolik Julia, Krause Freia, Stevanovic Marija, Gandraß Monja, Thomsen Ilka, Schacht Sarah-Sophie, Rieser Eva, Müller Miryam, Schumacher Neele, Fritsch Jürgen, Wichert Rielana, Galun Eithan, Bergmann Juri, Röder Christian, Schafmayer Clemens, Egberts Jan-Hendrik, Becker-Pauly Christoph, Saftig Paul, Lucius Ralph, Schneider-Brachert Wulf, Barikbin Roja, Adam Dieter, Voss Matthias, Hitzl Wolfgang, Krüger Achim, Strilic Boris, Sagi Irit, Walczak Henning, Rose-John Stefan, Schmidt-Arras Dirk
Аннотация
BACKGROUND AND AIM: Measles, mumps, and rubella vaccine (MMR) coverage is low in an area in the Northern part of Stockholm, Sweden. The overall aim of this study was to explore the perceptions, views, and experiences of child health clinic nurses related to vaccine hesitancy in Rinkeby and Tensta.
METHODS: The study focused specifically on hesitancy towards measles-mumps-rubella (MMR) vaccination. Eleven in-depth interviews were conducted in Swedish with female nurses who were directly responsible for vaccination programmes. Their thoughts and experiences were sought using probing and question rephrasing techniques. Transcripts of the data were analysed using content analysis.
RESULTS: Four themes emerged, namely hesitancy among Somali parents, lack of confidence in the MMR vaccine, loss of confidence in other vaccines due to mistrust of the MMR vaccine, and complacency regarding vaccination in general.
CONCLUSION: There is a strong influence of fear of vaccine-induced autism among parents in the Somali community in areas of Stockholm, that requires continued attention by the health care providers.
METHODS: The study focused specifically on hesitancy towards measles-mumps-rubella (MMR) vaccination. Eleven in-depth interviews were conducted in Swedish with female nurses who were directly responsible for vaccination programmes. Their thoughts and experiences were sought using probing and question rephrasing techniques. Transcripts of the data were analysed using content analysis.
RESULTS: Four themes emerged, namely hesitancy among Somali parents, lack of confidence in the MMR vaccine, loss of confidence in other vaccines due to mistrust of the MMR vaccine, and complacency regarding vaccination in general.
CONCLUSION: There is a strong influence of fear of vaccine-induced autism among parents in the Somali community in areas of Stockholm, that requires continued attention by the health care providers.
Предметные рубрики MeSH
ADAM17 ProteinAnimalsAntineoplastic AgentsBiomarkersBiomarkers, TumorCell CommunicationCell DeathDisease SusceptibilityEndothelial CellsHumansNecroptosisNeoplasm InvasivenessNeoplasm MetastasisNeoplasm SeedingNeoplasmsProteolysisReceptors, Tumor Necrosis Factor, Type ITumor MicroenvironmentTumor Necrosis Factor-alpha