An unusual false-positive uptake of radioiodine caused by pulmonary vasculature: The usefulness of SPECT/CT.

There are numerous conditions that may cause false-positive findings on iodine scintigraphy, such as vascular structure, mediastinum, bronchiectasis, cystic lesions and mature cystic teratoma; however, many of their mechanisms remain to be elucidated. Single photon emission tomography/computed tomography (SPECT/CT) imaging can be conducive to avoiding potential pitfalls. In addition, the nuclear physicians have to bear in mind that iodine-131 (131I) uptake in pulmonary vasculature can be a possible cause of false-positive uptake when they interpret 131I whole body scan (WBS).