Annals of palliative medicine · 2020
A survival analysis of patients with an acute exacerbation of chronic obstructive pulmonary disease discharged from the respiratory intensive care unit.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Cheng Jie, Lu Min, Sun Huijuan, Mao Yanjun
Аннотация
BACKGROUND: To analyse the survival of patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) after discharge from respiratory intensive care unit (RICU) and the adverse factors affecting patient's survival, so as to improve the follow-up work in the future.
METHODS: A retrospective observational study was conducted in the RICU. Patient demographic and clinical data were collected before discharge.
RESULTS: All patients were followed for 2 years after discharge. Living status was collected. The LogRank test was used to compare the survival distributions at 24 months, and the Kaplan-Meier curve was plotted. Multivariate Cox regression analysis was performed. A total of 159 patients were admitted to the RICU; 19 patients died in the hospital. The post-hospitalization mortality was 18.24% (29/159), 27.04% (43/159), and 37.11% (59/159), respectively, at 6, 12 and 24 months. Data from a total of 140 discharged patients were collected and analysed. Old age, no education, low BMI, bedridden status, comorbidity with bronchiectasis, and comorbidity with cancer were risk factors affecting the survival rate of patients with an acute exacerbation of chronic obstructive pulmonary disease (COPD) as analysed by the Log-Rank test. Multivariate Cox regression analysis showed that old age, no education, and low BMI were independent factors affecting patient survival.
CONCLUSIONS: In China, there are many older patients who have no education, and it may be very important for patients with an acute exacerbation of COPD to have additional specialized health education after discharge.
METHODS: A retrospective observational study was conducted in the RICU. Patient demographic and clinical data were collected before discharge.
RESULTS: All patients were followed for 2 years after discharge. Living status was collected. The LogRank test was used to compare the survival distributions at 24 months, and the Kaplan-Meier curve was plotted. Multivariate Cox regression analysis was performed. A total of 159 patients were admitted to the RICU; 19 patients died in the hospital. The post-hospitalization mortality was 18.24% (29/159), 27.04% (43/159), and 37.11% (59/159), respectively, at 6, 12 and 24 months. Data from a total of 140 discharged patients were collected and analysed. Old age, no education, low BMI, bedridden status, comorbidity with bronchiectasis, and comorbidity with cancer were risk factors affecting the survival rate of patients with an acute exacerbation of chronic obstructive pulmonary disease (COPD) as analysed by the Log-Rank test. Multivariate Cox regression analysis showed that old age, no education, and low BMI were independent factors affecting patient survival.
CONCLUSIONS: In China, there are many older patients who have no education, and it may be very important for patients with an acute exacerbation of COPD to have additional specialized health education after discharge.