Cornea · 2001
Hepatitis C-associated peripheral corneal ulceration: rapid response to intravenous steroids.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Pluznik D, Butrus S I
Аннотация
PURPOSE: We present a case of peripheral corneal ulceration in a patient with hepatitis C, which rapidly and dramatically responded to intravenous steroid treatment.
METHODS: Clinical examination and photographs were obtained to document initial presentation and therapeutic response of Mooren's-type ulcers to steroids.
RESULTS: Bilateral peripheral corneal ulceration with documented progression responded to intravenous administration of steroids within 5 days.
CONCLUSION: Previous reports of Mooren's-type ulcers in patients with chronic hepatitis C have shown a response to interferon alfa-2b, but not to oral corticosteroid therapy. Given the medical contraindications to interferon use in selected patients and the cost, we suggest a trial of high-dose systemic steroids as a possible therapy.
METHODS: Clinical examination and photographs were obtained to document initial presentation and therapeutic response of Mooren's-type ulcers to steroids.
RESULTS: Bilateral peripheral corneal ulceration with documented progression responded to intravenous administration of steroids within 5 days.
CONCLUSION: Previous reports of Mooren's-type ulcers in patients with chronic hepatitis C have shown a response to interferon alfa-2b, but not to oral corticosteroid therapy. Given the medical contraindications to interferon use in selected patients and the cost, we suggest a trial of high-dose systemic steroids as a possible therapy.